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Biological membranes are essential for life, acting as protective barriers that keep harmful substances out while serving as communication hubs through receptors and channels that regulate crucial cellular and extracellular processes. In addition to this, membranes create distinct compartments that allow vital but incompatible metabolic reactions to occur simultaneously within the cell.
In our lab, we develop and apply cutting-edge fluorescence microscopy and spectroscopy techniques to uncover key aspects of membrane biophysics, such as protein-lipid interactions, membrane structure and organization, and dynamic membrane behavior. Our goal is to gain a deeper understanding of how these membranes contribute to cellular function, both in health and in disease. Through this integration of biophysics and fluorescence microscopy, we are focused on the following research topics