2 Ph.D. positions for a single molecule fluorescence spectroscopy and microscopy
The role of cellular membranes goes far beyond protecting the integrity of the cell interior and separating it from the extracellular space. Its complex structure allows cells to communicate with the exterior and is also the site of key cellular regulatory processes that involve lipids, proteins and salt ions. In order to gain insight into these complex processes and potentially influence them therapeutically, an atomistic understanding is imperative.
The offered PhD positions are a part of two prestigious projects funded by Czech Science Foundation with the major aim to understand how the interplay between membranes with complex lipid composition and topology, and the regulatory effects of ions modulate the action of membrane proteins and other membrane processes. Within this project experiments performed in the Department of Biophysical Chemistry of Heyrovský Institute will be combined with computer simulations.
The candidates will use various advanced single molecule fluorescence techniques such as FCS (fluorescence correlation spectroscopy), SPT (single particle tracking), FRET (Förster resonance energy transfer) and various fluorescence imaging techniques. The candidates will be involved in all stages of the research including experimental work, analysis and interpretation of the obtained data, design of new experiments, scientific discussions and presentation at international conferences and publication of the achieved results. We are searching highly motivated candidates who would like to work in a world-wide respected biophysical research team.
General requirements
- Master degree in physics, chemistry or related fields.
- Good communication skills in written and spoken English.
- Previous experience with biophysical and biochemical methods including fluorescence techniques is of considerable benefit.
- Good programing skills in MATLAB or similar are welcome.
Type of contract: Temporary
Job status: Part-time
Offer starting date: October, 2022
Benefits
- 25 days paid leave of absence (holidays) per year + 3 days of paid sick-leave in addition to the statutory insurance
- Flexible working-time, the possibility of part-time work, work-life balance
- Lunch vouchers
- Subsidy for sport and cultural activities
- Recreation subsidy, recreation subsidy for children
- Possibility of attending children groups of the CAS
- Possibility to use discounts in recreation centers of the CAS
- Sports goods rental, free parking, trade union library
- Language courses
- Accommodation facilities
Eligibility criteria
To apply, please send a motivation letter with a CV and brief summary of previous research activities, a copy of your diploma, 1-2 references including their names, job titles, institution, address, email and phone number to recruitment
jh-inst.cas.cz and radek.sachljh-inst.cas.cz. Please, write in the subject line of your email SC2022_25. By submitting the application you confirm that all personal data you have sent to us are true.
By providing us your personal data in your CV, you have allowed J. Heyrovský Institute of Physical Chemistry to process and file your CV in the HR database. Your personal data will be used for the internal HR needs of the J. Heyrovský Institute of Physical Chemistry only. At the same time you confirm herewith that the personal data as stated in the CV you have sent to us is true and accurate.
